1,2-Octanediol, a Novel Surfactant, for Treating Head Louse Infestation: Identification of Activity, Formulation, and Randomised, Controlled Trials
نویسندگان
چکیده
منابع مشابه
1,2-Octanediol, a Novel Surfactant, for Treating Head Louse Infestation: Identification of Activity, Formulation, and Randomised, Controlled Trials
BACKGROUND Interest in developing physically active pediculicides has identified new active substances. The objective was to evaluate a new treatment for clinical efficacy. METHODS AND FINDINGS We describe the selection of 1,2-octanediol as a potential pediculicide. Clinical studies were community based. The main outcome measure was no live lice, after two treatments, with follow up visits ov...
متن کاملNeem-silicone lotion and ultrasound nit comb: a randomised, controlled clinical trial treating head louse infestation
Background: A neem-based conditioner lotion (ONC) used against head lice was previously tested clinically and shown to be relatively ineffective. To improve the activity against lice and their eggs, it was reformulated into a silicone vehicle (NNC) as part of a project to improve pediculicidal medical devices. An ultrasound nit comb was also developed to be used in conjunction with the neem lot...
متن کاملPrevention of head louse infestation: a randomised, double-blind, cross-over study of a novel concept product, 1% 1,2-octanediol spray versus placebo
OBJECTIVES To determine whether regular use of a spray containing 1,2-octanediol 1%, which has been shown to inhibit survival of head lice, is able to work as a preventive against establishment of new infestations. SETTING Randomised, double-blind, cross-over, community study in Cambridgeshire, UK. PARTICIPANTS 63 male and female schoolchildren aged 4-16 years judged to have a high risk of ...
متن کاملTreatment of head louse infestation with 4% dimeticone lotion: randomised controlled equivalence trial.
OBJECTIVE To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. DESIGN Randomised controlled equivalence trial. SETTING Community, with home visits. PARTICIPANTS 214 young people aged 4 to 18 years and 39 adults with active head louse infestation. INTERVENTIONS Two applications seven days apart of either 4.0% dimeticone lotion, applied for ...
متن کاملPrimary care Treatment of head louse infestation with 4% dimeticone lotion: randomised controlled equivalence trial
Objective To evaluate the efficacy and safety of 4% dimeticone lotion for treatment of head louse infestation. Design Randomised controlled equivalence trial. Setting Community, with home visits. Participants 214 young people aged 4 to 18 years and 39 adults with active head louse infestation. Interventions Two applications seven days apart of either 4.0% dimeticone lotion, applied for eight ho...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2012
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0035419